Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RORB | Q92753 | 5/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567678 | 0.78 | ADORA2A (0.48) | ADORA2AADORA1MAPTALDH1A1LMNA | |
| SCHEMBL8842777 | 0.72 | ADORA2A (0.45) | ADORA2AADORA1MAPTALDH1A1LMNA | |
| SCHEMBL8936345 | 0.71 | KMO (0.54) | ADORA2AADORA1ALDH1A1RORBKMO | |
| SCHEMBL8936334 | 0.69 | ADORA2A (0.51) | ADORA2AADORA1ALDH1A1RORBKMO | |
| SCHEMBL8842875 | 0.69 | ADORA2A (0.48) | ADORA2AADORA1ALDH1A1RORBKMO | |
| SCHEMBL6631083 | 0.69 | POLB (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| Bicarbonate SCHEMBL3262534 | 0.69 | NUDT1 (0.62) | ADORA2AADORA1KMOKMT2ADYRK1A | |
| SCHEMBL3545816 | 0.69 | LMNA (0.63) | MAPTALDH1A1LMNANPSR1KMT2A | |
| Urea SCHEMBL16246927 | 0.69 | KIF11 (0.67) | MAPTKMOKMT2AMEN1RAB9A | |
| SCHEMBL13734158 | 0.68 | BRD4 (0.53) | ADORA2AADORA1ALDH1A1RORBKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674887-A | Prevention of bone resorption | ELI LILLY AND COMPANY (US) | 1997-10-07 | — | — | US | disclosed |