Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 5/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19138009 | 0.80 | HTT (0.46) | HSD17B10HTTKDM4EALDH1A1 | |
| SCHEMBL3345499 | 0.78 | KMO (0.56) | KMOADORA1ADORA2AXDHRORB | |
| SCHEMBL8691066 | 0.77 | TDO2 (0.46) | KMOADORA1ADORA2AXDHRORB | |
| SCHEMBL9048030 | 0.77 | ADORA2A (0.48) | KMOADORA1ADORA2ARORBTDO2 | |
| SCHEMBL368305 | 0.77 | DHODH (0.47) | HSD17B10HTT | |
| SCHEMBL473595 | 0.77 | ALDH1A1 (0.59) | KMOXDHRORBTDO2KDM4E | |
| SCHEMBL10429353 | 0.76 | KDM4E (0.55) | KMOADORA1ADORA2ARORBTDO2 | |
| SCHEMBL13734158 | 0.76 | BRD4 (0.53) | KMOADORA1ADORA2AXDHRORB | |
| SCHEMBL9047986 | 0.76 | ADORA2A (0.48) | ADORA1ADORA2AXDHTDO2PIN1 | |
| SCHEMBL31606903 | 0.76 | ADORA2A (0.51) | ADORA1ADORA2AXDHTDO2KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031469-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |
| US-5541174-A | COORDINATION COMPOUND OF COPPER AND AN AMINO ACID | SORENSON JOHN R J (US) | 1996-07-30 | — | — | US | disclosed |
| US-5216021-A | Copper coordination compounds | SORENSON JOHN R J (US) | 1993-06-01 | — | — | US | disclosed |
| US-5082834-A | Antiarthritic agents, coordination compounds of copper and aci d salicylates | J.R.J. SORENSON CORP. | 1992-01-21 | — | — | US | disclosed |
| US-4440754-A | COPPER COORDINATION COMPOUNDS | J.R.J. SORENSON CORP. | 1984-04-03 | — | — | US | disclosed |
| US-4221785-A | COORDINATION COMPOUND OF A COPPER SALT AND A SALICYLIC ACID OR ITS DERIVATIVE | J.R.J. SORENSON CORP. | 1980-09-09 | — | — | US | disclosed |