Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.52 |
| ▸ | MMP13 | P45452 | 10/20 | 0.52 |
| ▸ | MMP9 | P14780 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212002 | 0.73 | NPC1 (0.51) | MMP1MMP13MMP9NPC1RAB9A | |
| SCHEMBL6962642 | 0.73 | NPC1 (0.55) | MMP1MMP13MMP9NPC1RAB9A | |
| SCHEMBL8559637 | 0.72 | MMP13 (0.72) | MMP1MMP13MMP9MMP3MMP2 | |
| SCHEMBL8713231 | 0.70 | MMP1 (0.73) | MMP1MMP13MMP9MMP3MMP2 | |
| SCHEMBL8843348 | 0.70 | MMP1 (0.51) | MMP1MMP13MMP9NPC1RAB9A | |
| SCHEMBL6929880 | 0.69 | MMP1 (0.76) | MMP1MMP13MMP9MMP3MMP2 | |
| SCHEMBL6617622 | 0.69 | MMP1 (0.50) | MMP1MMP13MMP9NPC1RAB9A | |
| SCHEMBL6381667 | 0.69 | NPC1 (0.56) | MMP1MMP13MMP9NPC1RAB9A | |
| SCHEMBL7383552 | 0.69 | ADAMTS4 (0.61) | MMP1MMP13MMP9NPC1RAB9A | |
| SCHEMBL7383553 | 0.69 | ADAMTS4 (0.61) | MMP1MMP13MMP9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |