Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881566 | 0.90 | ACHE (0.40) | ALDH1A1SMN1; SMN2HSD17B10ADORA3ADORA2B | |
| SCHEMBL8880275 | 0.88 | ADORA3 (0.35) | SMN1; SMN2NPSR1ADORA3ADORA2BGABRA1 | |
| SCHEMBL8880778 | 0.88 | MAPT (0.37) | ALDH1A1SMN1; SMN2HPGDNPSR1ADORA3 | |
| SCHEMBL8883880 | 0.87 | RAB9A (0.39) | ALDH1A1SMN1; SMN2HPGDHSD17B10ADORA3 | |
| SCHEMBL8098958 | 0.86 | ELANE (0.36) | ALDH1A1HPGDHSD17B10ADORA3ADORA2B | |
| SCHEMBL8012794 | 0.84 | ELANE (0.34) | ALDH1A1SMN1; SMN2ADORA3ADORA2BGABRA1 | |
| SCHEMBL8317836 | 0.84 | TSHR (0.36) | ALDH1A1SMN1; SMN2HPGDNPSR1HSD17B10 | |
| SCHEMBL8555959 | 0.84 | KIF11 (0.34) | POLB | |
| SCHEMBL8879965 | 0.83 | MAPT (0.46) | ALDH1A1SMN1; SMN2HPGDHSD17B10ADORA3 | |
| SCHEMBL8556161 | 0.83 | AADAT (0.34) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677306-A | ANTAGONIZING ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID RECEPTOR, USEFUL FOR TREATING ALL ISCHEMIAS | RHONE-POULENC RORER S.A. (FR) | 1997-10-14 | — | — | US | disclosed |