Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881566 | 0.90 | ACHE (0.40) | MAPTALDH1A1ADORA3ADORA2BGABRA1 | |
| SCHEMBL8879634 | 0.88 | ALDH1A1 (0.37) | MAPTALDH1A1NPSR1POLBKDM4E | |
| SCHEMBL8880275 | 0.88 | ADORA3 (0.35) | MAPTL3MBTL1NPSR1KDM4ELMNA | |
| SCHEMBL8883880 | 0.87 | RAB9A (0.39) | MAPTALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL8317836 | 0.86 | TSHR (0.36) | MAPTALDH1A1L3MBTL1NPSR1TSHR | |
| SCHEMBL8098958 | 0.86 | ELANE (0.36) | MAPTALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL8012794 | 0.84 | ELANE (0.34) | MAPTALDH1A1KDM4ECYP2C9ADORA3 | |
| SCHEMBL8557798 | 0.84 | KIF11 (0.36) | ALDH1A1KDM4EKIF11 | |
| SCHEMBL8879965 | 0.83 | MAPT (0.46) | MAPTALDH1A1L3MBTL1POLBKDM4E | |
| SCHEMBL8557277 | 0.83 | AADAT (0.34) | CYP3A4KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677306-A | ANTAGONIZING ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID RECEPTOR, USEFUL FOR TREATING ALL ISCHEMIAS | RHONE-POULENC RORER S.A. (FR) | 1997-10-14 | — | — | US | disclosed |