Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.36 |
| ▸ | ACACA | Q13085 | 4/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891432 | 0.93 | ALDH1A1 (0.37) | KEAP1NFE2L2TBXA2RALDH1A1LMNA | |
| SCHEMBL8891698 | 0.92 | GAA (0.39) | KEAP1NFE2L2NPSR1HSD17B10ACACA | |
| SCHEMBL8890090 | 0.91 | KEAP1 (0.39) | KEAP1NFE2L2NPSR1HSD17B10TBXA2R | |
| SCHEMBL8893753 | 0.89 | POLB (0.41) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL8892224 | 0.85 | NPSR1 (0.45) | KEAP1NFE2L2NPSR1HSD17B10TBXA2R | |
| SCHEMBL8892364 | 0.85 | KEAP1 (0.38) | KEAP1NFE2L2TBXA2RACACAACACB | |
| SCHEMBL8891690 | 0.85 | HTT (0.37) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL8892844 | 0.84 | ABCC9 (0.39) | KEAP1NFE2L2ALDH1A1LMNAGAA | |
| SCHEMBL8891927 | 0.84 | KEAP1 (0.37) | KEAP1NFE2L2NPSR1HSD17B10TBXA2R | |
| SCHEMBL8893620 | 0.83 | ALDH1A1 (0.34) | KEAP1NFE2L2NPSR1HSD17B10TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |