Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890978 | 0.91 | ABCC9 (0.47) | POLBL3MBTL1THRBALDH1A1KMT2A | |
| SCHEMBL8891432 | 0.91 | ALDH1A1 (0.37) | POLBALDH1A1KMT2ACNR1GAA | |
| SCHEMBL8892270 | 0.89 | KEAP1 (0.39) | POLBL3MBTL1ALDH1A1KMT2AGAA | |
| SCHEMBL8890086 | 0.89 | POLB (0.39) | POLBL3MBTL1THRBALDH1A1KMT2A | |
| SCHEMBL8891690 | 0.88 | HTT (0.37) | ALDH1A1KMT2ACNR1MEN1HTT | |
| SCHEMBL8891142 | 0.85 | HTT (0.35) | L3MBTL1ALDH1A1KMT2ACNR1MEN1 | |
| SCHEMBL8898777 | 0.84 | ALDH1A1 (0.41) | POLBL3MBTL1ALDH1A1TSHRABCC9 | |
| SCHEMBL8891705 | 0.84 | ALDH1A1 (0.39) | POLBL3MBTL1ALDH1A1KMT2ATSHR | |
| SCHEMBL8890408 | 0.83 | ALDH1A1 (0.39) | POLBL3MBTL1THRBALDH1A1KMT2A | |
| SCHEMBL8892844 | 0.82 | ABCC9 (0.39) | POLBALDH1A1KMT2ACNR1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |