Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893995 | 0.93 | ALDH1A1 (0.41) | TBXA2RACACBALDH1A1POLBKMT2A | |
| SCHEMBL8890852 | 0.91 | ABCC9 (0.38) | KEAP1NFE2L2ACACAACACBALDH1A1 | |
| SCHEMBL8890891 | 0.91 | KEAP1 (0.37) | KEAP1NFE2L2TBXA2RALDH1A1 | |
| SCHEMBL8891705 | 0.89 | ALDH1A1 (0.39) | ALDH1A1POLBMEN1KMT2AHTT | |
| SCHEMBL8893099 | 0.86 | POLB (0.41) | KEAP1NFE2L2TBXA2RALDH1A1POLB | |
| SCHEMBL8892270 | 0.85 | KEAP1 (0.39) | KEAP1NFE2L2TBXA2RACACAACACB | |
| SCHEMBL8890314 | 0.85 | L3MBTL1 (0.41) | KEAP1NFE2L2TBXA2RALDH1A1POLB | |
| SCHEMBL8891927 | 0.85 | KEAP1 (0.37) | KEAP1NFE2L2TBXA2RACACAACACB | |
| SCHEMBL8892494 | 0.84 | HTT (0.38) | ALDH1A1KMT2AHTT | |
| SCHEMBL8893286 | 0.84 | ALDH1A1 (0.40) | ALDH1A1POLBKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |