Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545815 | 0.82 | MAOB (0.42) | ALDH1A1 | |
| SCHEMBL8893376 | 0.82 | SIRT1 (0.41) | LMNAL3MBTL1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL9545818 | 0.81 | MAOB (0.44) | — | |
| SCHEMBL8893717 | 0.81 | SIRT1 (0.36) | LMNAGAAALDH1A1 | |
| SCHEMBL9202236 | 0.80 | SIRT1 (0.37) | GAAALDH1A1 | |
| SCHEMBL8466140 | 0.79 | L3MBTL1 (0.42) | LMNAGAATSHRL3MBTL1POLB | |
| SCHEMBL8903156 | 0.78 | L3MBTL1 (0.46) | LMNAL3MBTL1POLBMAPTALDH1A1 | |
| SCHEMBL8892678 | 0.78 | SIRT1 (0.36) | GAAMAPTALDH1A1RAB9A | |
| SCHEMBL9207805 | 0.78 | RAB9A (0.40) | RAB9A | |
| SCHEMBL8892119 | 0.77 | ADAM17 (0.36) | GAATSHRL3MBTL1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038997-A1 | SUBSTITUTED OXAZOLIDINEDIONES AND THEIR USE AS FUNGICIDES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |