Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545815 | 0.82 | MAOB (0.42) | SIRT1MMP2MMP13ALDH1A1ADAM17 | |
| SCHEMBL8893376 | 0.81 | SIRT1 (0.41) | SIRT1MMP2MMP13MMP9ADAM17 | |
| SCHEMBL9202236 | 0.81 | SIRT1 (0.37) | SIRT1MMP2MMP13ALDH1A1GAA | |
| SCHEMBL8892271 | 0.81 | LMNA (0.52) | ALDH1A1GAALMNA | |
| SCHEMBL8893414 | 0.80 | ADAM17 (0.36) | SIRT1MMP2MMP13ALDH1A1MMP9 | |
| SCHEMBL8903156 | 0.80 | L3MBTL1 (0.46) | SIRT1MMP2MMP13ALDH1A1LMNA | |
| SCHEMBL8892678 | 0.80 | SIRT1 (0.36) | SIRT1MMP2MMP13ALDH1A1GAA | |
| SCHEMBL9207805 | 0.79 | RAB9A (0.40) | SIRT1MMP2MMP13 | |
| SCHEMBL8902040 | 0.79 | SIRT1 (0.38) | SIRT1MMP2MMP13GAAMMP9 | |
| Famoxadone SCHEMBL673443 | 0.79 | MMP2 (0.42) | SIRT1MMP2MMP13ALDH1A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038997-A1 | SUBSTITUTED OXAZOLIDINEDIONES AND THEIR USE AS FUNGICIDES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |