Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893376 | 0.82 | SIRT1 (0.41) | SIRT1MMP1ADAM17MEN1KMT2A | |
| SCHEMBL8466140 | 0.81 | L3MBTL1 (0.42) | SIRT1MEN1KMT2AMAPK1RAB9A | |
| SCHEMBL9545815 | 0.81 | MAOB (0.42) | SIRT1MMP1ADAM17MEN1KMT2A | |
| SCHEMBL8903156 | 0.81 | L3MBTL1 (0.46) | SIRT1CYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL9202236 | 0.80 | SIRT1 (0.37) | SIRT1MMP1ADAM17MEN1KMT2A | |
| SCHEMBL8893717 | 0.80 | SIRT1 (0.36) | SIRT1ADAM17MMP2MMP13ALDH1A1 | |
| SCHEMBL8902452 | 0.79 | SIRT1 (0.39) | SIRT1MMP1ADAM17MEN1KMT2A | |
| SCHEMBL9207805 | 0.79 | RAB9A (0.40) | SIRT1MEN1KMT2AMMP2MMP13 | |
| SCHEMBL8892271 | 0.78 | LMNA (0.52) | RAB9AALDH1A1GAAMAPT | |
| SCHEMBL8902040 | 0.78 | SIRT1 (0.38) | SIRT1ADAM17CYP2C9CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |