Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902452 | 0.89 | SIRT1 (0.39) | SIRT1MMP2MMP13MMP9ADAM17 | |
| SCHEMBL8902040 | 0.87 | SIRT1 (0.38) | SIRT1MMP2MMP13MMP9ADAM17 | |
| SCHEMBL9545818 | 0.85 | MAOB (0.44) | SIRT1MMP2MMP13MMP9MMP1 | |
| SCHEMBL9545815 | 0.85 | MAOB (0.42) | SIRT1MMP2MMP13ADAM17MMP1 | |
| SCHEMBL8892678 | 0.82 | SIRT1 (0.36) | SIRT1MMP2MMP13ADAM17RAB9A | |
| SCHEMBL8903156 | 0.82 | L3MBTL1 (0.46) | SIRT1MMP2MMP13RAB9AL3MBTL1 | |
| SCHEMBL9207805 | 0.82 | RAB9A (0.40) | SIRT1MMP2MMP13NPC1RAB9A | |
| SCHEMBL9202236 | 0.82 | SIRT1 (0.37) | SIRT1MMP2MMP13MMP9ADAM17 | |
| SCHEMBL8892271 | 0.82 | LMNA (0.52) | RAB9ASMN1; SMN2L3MBTL1MAPTLMNA | |
| SCHEMBL8893717 | 0.81 | SIRT1 (0.36) | SIRT1MMP2MMP13MMP9ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |