Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.55 |
| ▸ | CTSB | P07858 | 5/20 | 0.55 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391841 | 0.96 | CTSK (0.56) | CTSKCTSBCTSSTACR1CTSL | |
| SCHEMBL8893516 | 0.91 | CASP3 (0.51) | CTSKCTSBCTSSTGM2CTSL | |
| SCHEMBL7388307 | 0.87 | CTSK (0.51) | CTSKCTSBCTSSCTSL | |
| SCHEMBL11780134 | 0.85 | ITGB3 (0.53) | CTSKCTSBCTSSCTSL | |
| SCHEMBL7432162 | 0.84 | CTSB (0.52) | CTSKCTSBCTSSCTSLMEN1 | |
| SCHEMBL27325266 | 0.80 | POLB (0.61) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL7266820 | 0.80 | POLB (0.61) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL7438999 | 0.79 | CTSS (0.55) | CTSKCTSBCTSSCTSLMEN1 | |
| SCHEMBL11778255 | 0.79 | TACR1 (0.74) | CTSKCTSBCTSSTGM2TACR1 | |
| SCHEMBL8895231 | 0.78 | CTSS (0.55) | CTSKCTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |
| US-3954731-A | Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids | ELI LILLY AND COMPANY (US) | 1976-05-04 | — | — | US | disclosed |