Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 8/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | MMP15 | P51511 | 1/20 | 0.34 |
| ▸ | MMP16 | P51512 | 1/20 | 0.34 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893403 | 0.90 | MAPT (0.36) | ADAM17MMP13SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8892119 | 0.81 | ADAM17 (0.36) | ADAM17MMP13TSHRALDH1A1MMP2 | |
| SCHEMBL8893717 | 0.80 | SIRT1 (0.36) | ADAM17MMP13ALDH1A1LMNAMMP2 | |
| SCHEMBL9545815 | 0.79 | MAOB (0.42) | ADAM17MMP13ALDH1A1MMP2MMP1 | |
| SCHEMBL8893376 | 0.79 | SIRT1 (0.41) | ADAM17MMP13SMN1; SMN2LMNAMMP2 | |
| SCHEMBL9545818 | 0.78 | MAOB (0.44) | MMP13MMP2MMP1MMP9SIRT1 | |
| SCHEMBL8466140 | 0.78 | L3MBTL1 (0.42) | SMN1; SMN2TSHRALDH1A1HTTLMNA | |
| SCHEMBL9202236 | 0.77 | SIRT1 (0.37) | ADAM17MMP13ALDH1A1MMP2MMP1 | |
| SCHEMBL8892271 | 0.76 | LMNA (0.52) | SMN1; SMN2TSHRALDH1A1LMNATDP1 | |
| SCHEMBL8903156 | 0.75 | L3MBTL1 (0.46) | MMP13ALDH1A1LMNAMMP2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |