SCHEMBL889502

SCHEMBL889502

CC(Br)C(=O)N(Cc1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.54
ALDH1A1 P00352 1/20 0.54
GLA P06280 1/20 0.54
HTT P42858 1/20 0.54
RAB9A P51151 1/20 0.54
PAX8 Q06710 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
LTB4R2 Q9NPC1 1/20 0.53
ATM Q13315 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TRPM8 Q7Z2W7 1/20 0.49
HPGD P15428 1/20 0.47
TSPO P30536 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12083234 0.91 PDK1 (0.48) NPC1ALDH1A1GLAHTTRAB9A
SCHEMBL12658891 0.86 LTB4R2 (0.68) NPC1ALDH1A1GLAHTTRAB9A
SCHEMBL10984675 0.83 ALDH1A1 (0.47) NPC1ALDH1A1GLAHTTRAB9A
SCHEMBL7497334 0.83 ALDH1A1 (0.61) ALDH1A1GLAHTTSMN1; SMN2HPGD
SCHEMBL11931984 0.82 ATM (0.58) NPC1ALDH1A1GLAHTTRAB9A
SCHEMBL13741509 0.82 ATM (0.58) NPC1ALDH1A1GLAHTTRAB9A
SCHEMBL11800781 0.81 MLYCD (0.48) ALDH1A1GLATSHR
SCHEMBL12679663 0.81 NPC1 (0.51) NPC1ALDH1A1GLAHTTRAB9A
SCHEMBL16297368 0.79 NPC1 (0.57) NPC1ALDH1A1GLAHTTRAB9A
SCHEMBL12679677 0.78 ATM (0.51) NPC1ALDH1A1GLAHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4061961-B1 METHOD FOR DOUBLE STRAND SEQUENCING OXFORD NANOPORE TECH PLC (GB) 2026-04-08 EP disclosed
US-20260072009-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-12 US disclosed
US-20260072008-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE UNIV OXFORD INNOVATION LTD (GB) 2026-03-12 US disclosed
US-20260063618-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE Oxford Nanopore Technolgies PLC (GB) 2026-03-05 US disclosed
EP-4689159-A1 METHOD AND KITS Oxford Nanopore Technologies PLC (GB) 2026-02-11 EP disclosed
EP-4270008-B1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE OXFORD NANOPORE TECH PLC (GB) 2026-02-04 EP disclosed
US-20260028379-A1 MUTANT PORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-01-29 US disclosed
US-12509721-B2 Methods and systems for characterizing analytes using nanopores OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-12-30 US disclosed
EP-4127711-B1 METHOD OF DETECTING AN ANALYTE IN A MEDIUM COMPRISING A LIGHT SCATTERING CONSTITUENT KING S COLLEGE LONDON (GB) 2025-12-24 EP disclosed
EP-4662489-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE Oxford University Innovation Limited (GB) 2025-12-17 EP disclosed
US-20210363577-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-11-25 US disclosed
WO-2021111139-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-06-10 WO disclosed
EP-3802877-A1 METHOD Oxford Nanopore Technologies Limited (GB) 2021-04-14 EP disclosed
CN-112189054-A Method of producing a composite material 牛津纳米孔科技公司 2021-01-05 CN disclosed
US-20190352709-A1 METHODS AND SYSTEMS FOR CHARACTERIZING ANALYTES USING NANOPORES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2019-11-21 US disclosed
EP-3548636-A1 METHODS AND SYSTEMS FOR CHARACTERIZING ANALYTES USING NANOPORES Oxford Nanopore Technologies Limited (GB) 2019-10-09 EP disclosed
US-20190202876-A1 MUTANT PORE OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2019-07-04 US disclosed
WO-2018100370-A1 METHODS AND SYSTEMS FOR CHARACTERIZING ANALYTES USING NANOPORES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2018-06-07 WO disclosed
US-20120010281-A1 ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-01-12 US disclosed
US-20120010281-A1 ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260072008-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE MAX, NPPA, NUP210 NPC1 1656/4885ALDH1A1 4882/4885GLA 4661/4885
US-12509721-B2 Methods and systems for characterizing analytes using nanopores DNA2, MTREX, DDX21 NPC1 953/4885ALDH1A1 2568/4885GLA 4601/4885
US-20260063618-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE NUP210, NPPA, NUP160 NPC1 147/4885ALDH1A1 4884/4885GLA 4714/4885
US-20260072009-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE NUP210, SLC9A2, SLC9A3 NPC1 613/4885ALDH1A1 4883/4885GLA 4666/4885
US-20260028379-A1 MUTANT PORE PTMS, NUP50, NUP205 NPC1 448/4885ALDH1A1 4884/4885GLA 3540/4885
US-20120010281-A1 ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS TBK1, TBCD, TBKBP1 NPC1 1385/4885ALDH1A1 3164/4885GLA 1172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.