Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821675 | 0.81 | TP53 (0.66) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL30421622 | 0.81 | TP53 (0.66) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| Propionic Acid SCHEMBL9592677 | 0.78 | ALOX15 (0.58) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| 1,2-Dichlorobenzene SCHEMBL29114306 | 0.77 | DAO (0.76) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL7201699 | 0.75 | L3MBTL1 (0.68) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL15979664 | 0.75 | ALDH1A1 (0.68) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL9465761 | 0.74 | TP53 (0.57) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL18050259 | 0.74 | MAPT (0.59) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL18050258 | 0.74 | MAPT (0.59) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL9148337 | 0.70 | LMNA (0.85) | TP53L3MBTL1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607334-B1 | CYCLIC UREAS AND ANALOGUES USEFUL AS RETROVIRAL PROTEASE INHIBITIORS | DU PONT MERCK PHARMA (US) | 1997-07-30 | — | — | EP | claimed |