Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467051 | 0.81 | LMNA (0.45) | TP53L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL30421622 | 0.78 | TP53 (0.66) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL9821675 | 0.78 | TP53 (0.66) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL8900631 | 0.74 | TP53 (0.60) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL15979664 | 0.73 | ALDH1A1 (0.68) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL7201699 | 0.73 | L3MBTL1 (0.68) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL18050259 | 0.72 | MAPT (0.59) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL18050258 | 0.72 | MAPT (0.59) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| 1,2-Dichlorobenzene SCHEMBL29114306 | 0.71 | DAO (0.76) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| Propionic Acid SCHEMBL9592677 | 0.70 | ALOX15 (0.58) | TP53L3MBTL1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252749-A | Binding to serotonin receptors 5HT3, 5HT1D and 5HT1B; hypotensive agents; cardiovascular and psychological disorders | ELF SANOFI (FR) | 1993-10-12 | — | — | US | disclosed |