Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900915 | 0.91 | PTGS2 (0.35) | HEXAHEXBPTGS2AURKASYK | |
| SCHEMBL8902933 | 0.87 | PTGS2 (0.35) | HEXAHEXBPTGS2AURKASYK | |
| SCHEMBL8900869 | 0.86 | PDE5A (0.40) | PTGS2AURKASYKAURKBMETAP2 | |
| SCHEMBL11965008 | 0.86 | MAPT (0.43) | HEXAHEXBALOX15AKR1B1KDM4E | |
| SCHEMBL11965009 | 0.84 | HEXA (0.40) | HEXAHEXBALOX15PTGS2ESR1 | |
| SCHEMBL8902940 | 0.83 | METAP2 (0.38) | PTGS2AURKASYKAURKBMETAP2 | |
| SCHEMBL8902356 | 0.83 | HEXA (0.38) | HEXAHEXBALOX15AKR1B1KDM4E | |
| SCHEMBL8902391 | 0.82 | ALDH1A1 (0.46) | HEXAHEXBALOX15PDE5AAKR1B1 | |
| SCHEMBL8903094 | 0.81 | GABRA1 (0.35) | PTGS2AURKASYKAURKBMETAP2 | |
| SCHEMBL8901216 | 0.80 | CASR (0.44) | HEXAHEXBALOX15TACR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188008-B2 | Herbicidally and insecticidally active 4-phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173775-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE 4-PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX4, PRDX1 | HEXA 1107/4885HEXB 585/4885ALOX15 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.