Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893376 | 0.89 | SIRT1 (0.41) | SIRT1ADAM17MMP2MMP9MMP13 | |
| SCHEMBL8902040 | 0.84 | SIRT1 (0.38) | SIRT1ADAM17MMP2MMP9MMP13 | |
| SCHEMBL9545818 | 0.80 | MAOB (0.44) | SIRT1MMP2MMP9MMP13MMP1 | |
| SCHEMBL9545815 | 0.79 | MAOB (0.42) | SIRT1ADAM17MMP2MMP13MMP1 | |
| SCHEMBL8892678 | 0.79 | SIRT1 (0.36) | SIRT1ADAM17MMP2MMP13MAPT | |
| SCHEMBL8903156 | 0.79 | L3MBTL1 (0.46) | SIRT1MMP2MMP13MAPTMEN1 | |
| SCHEMBL9202236 | 0.79 | SIRT1 (0.37) | SIRT1ADAM17MMP2MMP9MMP13 | |
| SCHEMBL8902120 | 0.79 | SPHK2 (0.49) | PPARA | |
| SCHEMBL8893717 | 0.78 | SIRT1 (0.36) | SIRT1ADAM17MMP2MMP9MMP13 | |
| SCHEMBL8892271 | 0.77 | LMNA (0.52) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |