Phosphoric Acid

Phosphoric Acid

SCHEMBL890455

C=C(C(=O)O)C(CCO)CCO.O=P(O)(O)O

nearest known ligand 0.40

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.32
FOLH1 Q04609 4/20 0.31
GRM3 Q14832 2/20 0.31
NAALAD2 Q9Y3Q0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2996538 0.91 TET2 (0.31)
SCHEMBL3665140 0.84
SCHEMBL1006025 0.84 PGK1 (0.34) PEPD
SCHEMBL1173517 0.81 CHRM1 (0.48)
SCHEMBL1782902 0.78 CA2 (0.39)
Phosphoric Acid SCHEMBL2993369 0.75 LMNA (0.31) PEPD
SCHEMBL2107092 0.75 CA2 (0.46)
Phosphoric Acid SCHEMBL23531687 0.72 FDPS (0.43)
SCHEMBL2047389 0.72
SCHEMBL10947964 0.71 CHRM1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7828550-B2 Activating endodontic points and dental tools for initiating polymerization of dental compositions ULTRADENT PRODUCTS, INC. (US) 2010-11-09 US claimed
EP-1926448-A2 COMPOSITIONS, KITS AND METHODS FOR INITIATING OR ACCELERATING CURING OF ENDODONTIC FILLER OR SEALER COMPOSITIONS PLACED ON A ROOT CANAL Ultradent Products, Inc. (US) 2008-06-04 EP claimed
WO-2007038051-A2 COMPOSITIONS, KITS AND METHODS FOR INITIATING OR ACCELERATING CURING OF ENDODONTIC FILLER OR SEALER COMPOSITIONS PLACED ON A ROOT CANAL ULTRADENT PRODUCTS, INC. (US) 2007-04-05 WO claimed
US-20070065781-A1 Activating endodontic points and dental tools for initiating polymerization of dental compositions ULTRADENT PRODUCTS, INC. 2007-03-22 US claimed
EP-0981273-A4 ADHESIVE, ANTIMICROBIAL AND/OR REPARATIVE DENTIN STIMULATING DENTAL COMPOSITIONS AND METHODS FOR FORMING AND USING SUCH COMPOSITIONS ULTRADENT PRODUCTS INC (US) 2004-12-01 EP claimed
US-6811400-B2 Method for filling and sealing a root canal ULTRADENT PRODUCTS, INC. 2004-11-02 US claimed
US-6756417-B2 WHEREIN HARDENING/CURING/PHOTOPOLYMERIZATION TAKES PLACE AT DIFFERENT STEPS; IMPROVED REPAIRING OF DECAYED/DAMAGED CHILDREN'S TEETH ULTRADENT PRODUCTS, INC. 2004-06-29 US claimed
US-6729879-B2 Dental bonding methods for adhering amalgam restoratives to dental substrates ULTRADENT PRODUCTS, INC. 2004-05-04 US claimed
US-6652282-B2 Endodontic sealing compositions and methods for using such compositions ULTRADENT PRODUCTS, INC. 2003-11-25 US claimed
US-20030199600-A1 Dental bonding compositions for adhering amalgam restoratives to dental substrates ULTRADENT PRODUCTS, INC.; 2003-10-23 US claimed
US-20030194682-A1 Method for filling and sealing a root canal JENSEN STEVEN D (US) 2003-10-16 US claimed
US-20030186197-A1 Dental bonding methods for adhering amalgam restoratives to dental substrates ULTRADENT PRODUCTS, INC. 2003-10-02 US claimed
US-6500004-B2 FOR SEALING A ROOT CANAL; INCLUDE RESINS THAT PROMOTE ADHESION TO HYDROPHILIC DENTAL TISSUES SUCH AS ALKYL METHACRYLATES AND DERIVATIVES THEREOF, SUCH AS OXYPHOSPHORO METHACRYLATES ULTRADENT PRODUCTS, INC. 2002-12-31 US claimed
US-20020177100-A1 Endodontic sealing compositions and methods for using such compositions JENSEN STEVEN D (US) 2002-11-28 US claimed
US-20020123024-A1 Endodontic sealing compositions and methods for using such compositions ULTRADENT PRODUCTS, INC. 2002-09-05 US claimed
WO-2002047572-A1 ENDODONTIC SEALING COMPOSITIONS AND METHODS FOR USING SUCH COMPOSITIONS ULTRADENT PRODUCTS, INC. (US) 2002-06-20 WO claimed
US-6309221-B1 A KIT INCLUDING PROPYLHEXEDRINE AND AT LEAST ONE IN-SITU POLYMERIZABLE MONOMER (PREFERABLY A PHOPHOALKYL ESTER OF METHACRYLIC ACID) CAPABLE OF ADHERING TO DENTIN AND BECOMING A BARRIER TO MICROORGANISMS ULTRADENT PRODUCTS, INC. 2001-10-30 US claimed
US-6071528-A CURABLE PHOSPHATE OR PHOSPHONATE ESTER OF (POLY)HYDROXYALKYL METHACRYLATE MONOMER; BONDING AND TENSILE STRENGTH; ULTRADENT PRODUCTS, INC. (US) 2000-06-06 US claimed
EP-0981273-A1 ADHESIVE, ANTIMICROBIAL AND/OR REPARATIVE DENTIN STIMULATING DENTAL COMPOSITIONS AND METHODS FOR FORMING AND USING SUCH COMPOSITIONS Ultradent Products, Inc. (US) 2000-03-01 EP claimed
WO-1998036639-A1 ADHESIVE, ANTIMICROBIAL AND/OR REPARATIVE DENTIN STIMULATING DENTAL COMPOSITIONS AND METHODS FOR FORMING AND USING SUCH COMPOSITIONS ULTRADENT PRODUCTS, INC. (US) 1998-08-27 WO claimed