Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802356 | 0.77 | ALOX15 (0.44) | MAPTALDH1A1POLBALOX15KMT2A | |
| SCHEMBL8352074 | 0.74 | MTNR1A (0.49) | MAPTKDM4EHTTALOX15KMT2A | |
| SCHEMBL8905474 | 0.72 | PPARG (0.44) | — | |
| SCHEMBL114035 | 0.70 | CASP1 (0.56) | MAPTALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL1866841 | 0.70 | CASP1 (0.56) | MAPTALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL12989157 | 0.69 | ALOX15 (0.61) | MAPTALDH1A1KDM4EALOX15KMT2A | |
| SCHEMBL1396715 | 0.66 | ALDH1A1 (0.64) | ALDH1A1POLBALOX15KMT2AGAA | |
| SCHEMBL28775761 | 0.66 | ALOX15 (0.61) | MAPTALDH1A1KDM4EALOX15KMT2A | |
| SCHEMBL839157 | 0.66 | ALOX15 (0.73) | MAPTALDH1A1ALOX15KMT2ACYP1A2 | |
| SCHEMBL28425775 | 0.66 | RAB9A (0.64) | MAPTALDH1A1KDM4EALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |