SCHEMBL839157

SCHEMBL839157

O=C(O)COC(=O)COc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.73
PAM P19021 1/20 0.58
FFAR1 O14842 1/20 0.55
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
PTPN7 P35236 2/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
PTPN12 Q05209 1/20 0.53
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.51
CASP1 P29466 1/20 0.51
ALPL P05186 1/20 0.49
ALPI P09923 1/20 0.49
ALPG P10696 1/20 0.49
LMNA P02545 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8127 0.85 ALOX15 (1.00) ALOX15FFAR1MEN1KMT2APTPN7
SCHEMBL1318870 0.85 ALOX15 (1.00) ALOX15FFAR1MEN1KMT2APTPN7
SCHEMBL12989157 0.84 ALOX15 (0.61) ALOX15MEN1KMT2AALDH1A1MAPT
SCHEMBL28425775 0.84 RAB9A (0.64) ALOX15MEN1KMT2AALDH1A1MAPT
SCHEMBL28775761 0.84 ALOX15 (0.61) ALOX15MEN1KMT2AALDH1A1MAPT
SCHEMBL10771804 0.83 ALOX15 (0.60) ALOX15FFAR1MEN1KMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL6844286 0.83 ALOX15 (0.95) ALOX15FFAR1MEN1KMT2APTPN7
Hydrochloric Acid SCHEMBL7049631 0.83 ALOX15 (0.95) ALOX15FFAR1MEN1KMT2APTPN7
SCHEMBL2168445 0.83 ALOX15 (0.95) ALOX15FFAR1MEN1KMT2APTPN7
Methane SCHEMBL7339930 0.83 ALOX15 (0.95) ALOX15FFAR1MEN1KMT2APTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160023997-A1 ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF BEZWADA BIOMEDICAL LLC (US) 2016-01-28 US disclosed
US-20150080301-A1 ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF BEZWADA BIOMEDICAL LLC (US) 2015-03-19 US disclosed
US-8901347-B1 Absorbable polyurethanes and methods of use thereof BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 US disclosed
US-8846845-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL, LLC (US) 2014-09-30 US disclosed
US-20120158127-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL, LLC (US) 2012-06-21 US disclosed
US-8143325-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL, LLC (US) 2012-03-27 US disclosed
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120158127-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES HAO2, AOC2, AOC1 ALOX15 300/4885PAM 66/4885FFAR1 2685/4885
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES ALOX12, HAO2, ALOX15 ALOX15 3/4885PAM 39/4885FFAR1 2348/4885
US-20150080301-A1 ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF HPGDS, ITGAM, P4HTM ALOX15 309/4885PAM 1589/4885FFAR1 2047/4885
US-20160023997-A1 ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF HPGDS, ITGAM, P4HTM ALOX15 309/4885PAM 1589/4885FFAR1 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.