Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906990 | 0.94 | ALOX5 (0.42) | ALOX5PTGESL3MBTL1 | |
| SCHEMBL8907331 | 0.93 | ALOX5 (0.40) | ALOX5PTGESAGTR1 | |
| SCHEMBL8905567 | 0.90 | KEAP1 (0.42) | ALOX5PTGES | |
| SCHEMBL8907073 | 0.87 | PTPN22 (0.43) | ALOX5PTGES | |
| SCHEMBL8905550 | 0.86 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8905540 | 0.85 | AGTR1 (0.41) | ALOX5PTGESAGTR1AGTR2 | |
| SCHEMBL8906118 | 0.84 | PPARG (0.37) | AGTR1AGTR2 | |
| SCHEMBL8905756 | 0.84 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8906787 | 0.82 | AGTR2 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8905446 | 0.80 | AGTR1 (0.38) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |