Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906990 | 0.97 | ALOX5 (0.42) | KEAP1NFE2L2BMP1CNR2PTPN22 | |
| SCHEMBL8907331 | 0.93 | ALOX5 (0.40) | ALOX5PTGES | |
| SCHEMBL8905536 | 0.90 | ALOX5 (0.44) | ALOX5PTGES | |
| SCHEMBL8907073 | 0.85 | PTPN22 (0.43) | CNR2PTPN22ALOX5PTGES | |
| SCHEMBL8905550 | 0.83 | AGTR1 (0.37) | — | |
| SCHEMBL8906118 | 0.82 | PPARG (0.37) | PPARGEDNRA | |
| SCHEMBL8905756 | 0.81 | AGTR1 (0.37) | — | |
| SCHEMBL8906787 | 0.79 | AGTR2 (0.37) | — | |
| SCHEMBL8906709 | 0.78 | PPARG (0.42) | CNR2ALDH1A1PPARGEDNRA | |
| SCHEMBL9094465 | 0.78 | PPARG (0.66) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |