Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907073 | 0.89 | PTPN22 (0.43) | MEN1KMT2A | |
| SCHEMBL8907331 | 0.85 | ALOX5 (0.40) | MEN1KMT2AAGTR1 | |
| SCHEMBL8905536 | 0.84 | ALOX5 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8906787 | 0.83 | AGTR2 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8905887 | 0.83 | EDNRA (0.37) | PPARGMEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL8905567 | 0.82 | KEAP1 (0.42) | PPARGEDNRA | |
| SCHEMBL8906990 | 0.82 | ALOX5 (0.42) | PPARGEDNRA | |
| SCHEMBL8905550 | 0.80 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8905756 | 0.79 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9095487 | 0.77 | PPARG (0.66) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |