Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905567 | 0.93 | KEAP1 (0.42) | ALOX5PTGES | |
| SCHEMBL8905536 | 0.93 | ALOX5 (0.44) | ALOX5PTGESAGTR1 | |
| SCHEMBL8906990 | 0.89 | ALOX5 (0.42) | ALOX5PTGES | |
| SCHEMBL8907073 | 0.87 | PTPN22 (0.43) | ALOX5PTGESMEN1KMT2A | |
| SCHEMBL8905550 | 0.85 | AGTR1 (0.37) | AGTR1 | |
| SCHEMBL8906118 | 0.85 | PPARG (0.37) | AGTR1MEN1KMT2A | |
| SCHEMBL8905756 | 0.83 | AGTR1 (0.37) | AGTR1 | |
| SCHEMBL8906787 | 0.81 | AGTR2 (0.37) | AGTR1 | |
| SCHEMBL8905540 | 0.78 | AGTR1 (0.41) | ALOX5PTGESAGTR1 | |
| SCHEMBL9095186 | 0.77 | AGTR1 (0.62) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |