Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905805 | 0.87 | LMNA (0.38) | ALDH1A1HPGDRAB9ANPC1HTT | |
| SCHEMBL8905900 | 0.86 | LMNA (0.37) | HPGDMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL8905938 | 0.86 | MEN1 (0.38) | ALDH1A1HPGDNPC1HTTSMN1; SMN2 | |
| SCHEMBL8904194 | 0.86 | CCNA2 (0.38) | ALDH1A1HPGDMAPTRAB9AHTT | |
| SCHEMBL8906156 | 0.86 | ALDH1A1 (0.35) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL9030270 | 0.85 | PDE3B (0.42) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL8904850 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL8904626 | 0.84 | CYP1A2 (0.48) | HPGDKMT2AMEN1NFKB1NPSR1 | |
| SCHEMBL8904827 | 0.84 | PDE3B (0.36) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL8904574 | 0.84 | NPC1 (0.42) | ALDH1A1HPGDRAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622948-A | ANALGESICS | SYNTEX (U.S.A.) INC. (US) | 1997-04-22 | — | — | US | disclosed |
| EP-0714895-A1 | Pyrrole derivatives | F. Hoffmann-La Roche AG (CH) | 1996-06-05 | — | — | EP | disclosed |