SCHEMBL8906285

SCHEMBL8906285

CC(C)N(CCCN(C)C)CCCN(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
DNM1 Q05193 3/20 0.39
TDP1 Q9NUW8 3/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
MAPT P10636 1/20 0.32
USP2 O75604 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26267223 0.90 ALDH1A1 (0.39) ALDH1A1TSHRDNM1
SCHEMBL25777500 0.90 ALDH1A1 (0.39) ALDH1A1TSHRDNM1
SCHEMBL26243208 0.90 DNM1 (0.44) ALDH1A1TSHRDNM1CYP1A2CYP2D6
SCHEMBL26239799 0.88 ALDH1A1 (0.38) ALDH1A1TSHRDNM1HTR2AHRH1
SCHEMBL13397468 0.87 ALDH1A1 (0.41) ALDH1A1TSHRDNM1HTR2AHRH1
SCHEMBL26350756 0.84 ALDH1A1 (0.35) ALDH1A1TSHRDNM1
SCHEMBL23791944 0.83 ALDH1A1 (0.43) ALDH1A1TSHRDNM1HTR2AHRH1
SCHEMBL26355365 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL10289401 0.81 CA12 (0.44) ALDH1A1TSHRDNM1TDP1CA12
SCHEMBL571029 0.78 ALDH1A1 (0.43) ALDH1A1TSHRDNM1TDP1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3259293-B1 TEMPERATURE-RESISTANT ISOCYANATE-BASED FOAMS HAVING A HIGH FLAME RESISTANCE BASF SE (DE) 2021-08-04 EP claimed
EP-2930219-A1 Reactive adhesive systems and their use Jowat AG (DE) 2015-10-14 EP claimed
US-20230285310-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM ARES CAPITAL CORPORATION, AS AGENT 2023-09-14 US disclosed
US-20230285310-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM ARES CAPITAL CORPORATION, AS AGENT 2023-09-14 US disclosed
WO-2023154818-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2023-08-17 WO disclosed
US-10626223-B2 Polyurethane-organopolysiloxanes RUDOLF GMBH (DE) 2020-04-21 US disclosed
EP-2930219-B1 Reactive adhesive systems and their use JOWAT AG (DE) 2018-12-26 EP disclosed
US-20180155503-A1 POLYURETHANE-ORGANOPOLYSILOXANES RUDOLF GMBH (DE) 2018-06-07 US disclosed
US-9642804-B2 Cationic lipids with various head groups for oligonucleotide delivery SIRNA THERAPEUTICS, INC. (US) 2017-05-09 US disclosed
US-9642804-B2 Cationic lipids with various head groups for oligonucleotide delivery SIRNA THERAPEUTICS, INC. (US) 2017-05-09 US disclosed
US-20160113874-A1 NOVEL CATATONIC LIPIDS WITH VARIOUS HEAD GROUPS FOR OLIGONUCLEOTIDE DELIVERY BANK OF AMERICA, N.A. 2016-04-28 US disclosed
US-9181295-B2 Cationic lipids with various head groups for oligonucleotide delivery SIRNA THERAPEUTICS, INC. (US) 2015-11-10 US disclosed
EP-2930219-A1 Reactive adhesive systems and their use Jowat AG (DE) 2015-10-14 EP disclosed
US-20120322721-A1 DRY GROWTH HORMONE COMPOSITION TRANSIENTLY LINKED TO A POLYMER CARRIER ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) 2012-12-20 US disclosed
US-20120253032-A1 NOVEL CATIONIC LIPIDS WITH SHORT LIPID CHAINS FOR OLIGONUCLEOTIDE DELIVERY MERCK SHARP & DOHME CORPORATION 2012-10-04 US disclosed
US-20120149894-A1 NOVEL CATIONIC LIPIDS WITH VARIOUS HEAD GROUPS FOR OLIGONUCLEOTIDE DELIVERY BANK OF AMERICA, N.A. 2012-06-14 US disclosed
US-20120149894-A1 NOVEL CATIONIC LIPIDS WITH VARIOUS HEAD GROUPS FOR OLIGONUCLEOTIDE DELIVERY BANK OF AMERICA, N.A. 2012-06-14 US disclosed
US-8119654-B2 Indenoisoquinolinone analogs and methods of use thereof INOTEK PHARMACEUTICALS CORPORATION (US) 2012-02-21 US disclosed
US-5693686-A RIGID, LOW-DENSITY POLYURETHANE FOAMS USING AN ACIDIC POLYISOCYANATE MONOMER TO STABILIZE THE BLOWING AGENTS BAYER CORPORATION (US) 1997-12-02 US disclosed
US-5464560-A Polyurethanes BAYER CORPORATION (US) 1995-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160113874-A1 NOVEL CATATONIC LIPIDS WITH VARIOUS HEAD GROUPS FOR OLIGONUCLEOTIDE DELIVERY NPC1L1, NPC1, ABCB4 ALDH1A1 4279/4885TSHR 1921/4885DNM1 266/4885
US-20120322721-A1 DRY GROWTH HORMONE COMPOSITION TRANSIENTLY LINKED TO A POLYMER CARRIER GHRHR, GHSR, GCG ALDH1A1 4509/4885TSHR 132/4885DNM1 4847/4885
US-20120253032-A1 NOVEL CATIONIC LIPIDS WITH SHORT LIPID CHAINS FOR OLIGONUCLEOTIDE DELIVERY NPC1L1, LDLR, NPC1 ALDH1A1 4810/4885TSHR 2290/4885DNM1 476/4885
US-20230285310-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM CFTR, TSLP, MTREX ALDH1A1 3126/4885TSHR 2383/4885DNM1 704/4885
US-20120149894-A1 NOVEL CATIONIC LIPIDS WITH VARIOUS HEAD GROUPS FOR OLIGONUCLEOTIDE DELIVERY NPC1L1, NPC1, LDLR ALDH1A1 4850/4885TSHR 1615/4885DNM1 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.