Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288721 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL14507692 | 0.69 | ACHE (0.32) | ACHE | |
| SCHEMBL8213378 | 0.69 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL22991536 | 0.68 | — | — | |
| SCHEMBL8935421 | 0.67 | ACHE (0.31) | ACHE | |
| SCHEMBL31013129 | 0.65 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL25348552 | 0.64 | TDP1 (0.33) | KDM4EALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL19983746 | 0.64 | IMPDH2 (0.35) | TDP1 | |
| SCHEMBL1530694 | 0.60 | TTR (0.48) | KDM4EALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL22893441 | 0.59 | CA2 (0.37) | KDM4EALDH1A1MAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620677-A | CONTRAST AGENTS IN DIAGNOSTIC RADIOLOGY | STERLING WINTHROP INC. (US) | 1997-04-15 | — | — | US | disclosed |