Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908407 | 0.81 | ALDH1A1 (0.39) | CACNA1GALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL8908933 | 0.80 | HTR2C (0.40) | CACNA1GALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL8908855 | 0.79 | CYP1A2 (0.44) | RAB9ACACNA1GALDH1A1POLBGAA | |
| SCHEMBL8908448 | 0.76 | ALDH1A1 (0.43) | CACNA1GALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL8909181 | 0.73 | HTR2C (0.49) | ALDH1A1POLBKMT2AMEN1DRD3 | |
| SCHEMBL11276187 | 0.71 | RAB9A (0.51) | RAB9ACACNA1GALDH1A1POLBGAA | |
| SCHEMBL8175607 | 0.66 | OPRM1 (0.78) | ALDH1A1NPSR1KMT2AMEN1DRD3 | |
| SCHEMBL7977689 | 0.66 | OPRM1 (0.78) | ALDH1A1NPSR1KMT2AMEN1DRD3 | |
| SCHEMBL3919536 | 0.66 | OPRM1 (0.78) | ALDH1A1NPSR1KMT2AMEN1DRD3 | |
| SCHEMBL8186671 | 0.66 | OPRM1 (0.78) | ALDH1A1NPSR1KMT2AMEN1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682657-B1 | 9H-INDENO[1,2-b]PYRAZINE-3(4H)-ONES AND 9H-INDENO[1,2-b]PYRAZINE-2,3(1H,4H)-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-11-19 | — | — | EP | claimed |