Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909107 | 0.81 | TSHR (0.33) | ALDH1A1HTT | |
| SCHEMBL8907599 | 0.79 | CYP1A2 (0.38) | ALDH1A1GAAHTT | |
| SCHEMBL8907689 | 0.66 | SERPINE1 (0.36) | ALDH1A1 | |
| SCHEMBL8907884 | 0.66 | S100A4 (0.36) | ALDH1A1 | |
| SCHEMBL8908279 | 0.63 | RAB9A (0.46) | ALDH1A1GAACACNA1G | |
| SCHEMBL2421009 | 0.62 | HRH1 (0.54) | ALDH1A1HTT | |
| SCHEMBL8908307 | 0.61 | ACP3 (0.40) | ALDH1A1 | |
| SCHEMBL4220332 | 0.60 | HRH1 (0.52) | ALDH1A1HTT | |
| SCHEMBL8474694 | 0.60 | DHODH (0.40) | ALDH1A1HTT | |
| SCHEMBL14814338 | 0.58 | HRH1 (0.45) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682657-B1 | 9H-INDENO[1,2-b]PYRAZINE-3(4H)-ONES AND 9H-INDENO[1,2-b]PYRAZINE-2,3(1H,4H)-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-11-19 | — | — | EP | claimed |