Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908817 | 0.84 | REN (0.38) | RENPSMB8PSMB5PSMB9PSMB10 | |
| SCHEMBL8910208 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL8910706 | 0.73 | F2R (0.38) | RENF2R | |
| SCHEMBL8910205 | 0.71 | GPR132 (0.36) | REN | |
| SCHEMBL8910252 | 0.67 | KDM4E (0.39) | REN | |
| SCHEMBL8909461 | 0.67 | REN (0.33) | REN | |
| Hydrochloric Acid SCHEMBL9800528 | 0.66 | REN (0.52) | REN | |
| SCHEMBL9800601 | 0.63 | REN (0.48) | REN | |
| SCHEMBL9800598 | 0.63 | REN (0.48) | REN | |
| SCHEMBL8910133 | 0.62 | REN (0.51) | RENPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |