Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
| ▸ | CYCS | P99999 | 3/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034725 | 0.93 | STAT3 (0.47) | STAT3STAT1TOP1CYCSSMAD3 | |
| SCHEMBL3125425 | 0.89 | STAT3 (0.49) | STAT3STAT1TOP1CYCSSMAD3 | |
| SCHEMBL80002 | 0.87 | STAT3 (0.48) | STAT3STAT1TOP1CYCS | |
| SCHEMBL460557 | 0.83 | STAT3 (0.50) | STAT3STAT1 | |
| SCHEMBL455573 | 0.83 | STAT3 (0.67) | STAT3STAT1TOP1CYCS | |
| SCHEMBL351526 | 0.81 | STAT3 (0.43) | STAT3STAT1TOP1CYCS | |
| SCHEMBL6092415 | 0.81 | STAT3 (0.43) | STAT3STAT1TOP1CYCS | |
| SCHEMBL8977875 | 0.79 | STAT3 (0.69) | STAT3STAT1TOP1CYCS | |
| SCHEMBL10523389 | 0.79 | STAT3 (0.36) | STAT3STAT1TOP1CYCS | |
| SCHEMBL6014909 | 0.78 | STAT3 (0.36) | STAT3STAT1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882234-A | TUMOR IMAGING AND PHOTODYNAMIC THERAPY AGENTS | HEALUX, INC. (US) | 1989-11-21 | — | — | US | claimed |
| EP-0539960-B1 | Hematoporphyrin derivatives complex salts and their use in the detection and treatment of neoplasms | WOJSKOWA AKAD TECH (PL) | 1997-03-05 | — | — | EP | disclosed |
| US-4882234-A | TUMOR IMAGING AND PHOTODYNAMIC THERAPY AGENTS | HEALUX, INC. (US) | 1989-11-21 | — | — | US | disclosed |
| US-4882234-A | TUMOR IMAGING AND PHOTODYNAMIC THERAPY AGENTS | HEALUX, INC. (US) | 1989-11-21 | — | — | US | disclosed |