Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | CYCS | P99999 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460557 | 0.95 | STAT3 (0.50) | STAT3STAT1 | |
| SCHEMBL8909390 | 0.87 | STAT3 (0.42) | STAT3STAT1TOP1CYCS | |
| SCHEMBL8160339 | 0.86 | STAT3 (0.71) | STAT3STAT1TOP1CYCS | |
| SCHEMBL1343985 | 0.79 | STAT3 (0.48) | STAT3STAT1TOP1 | |
| SCHEMBL868308 | 0.79 | STAT3 (0.48) | STAT3STAT1 | |
| SCHEMBL869195 | 0.79 | STAT3 (0.48) | STAT3STAT1 | |
| SCHEMBL224519 | 0.79 | STAT3 (0.48) | STAT3STAT1 | |
| SCHEMBL9866324 | 0.79 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL6479855 | 0.79 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL38329 | 0.79 | STAT3 (0.49) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140106367-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-04-17 | — | — | US | disclosed |
| US-8530459-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-09-10 | — | — | US | disclosed |
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120126214-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | UNITED STATES DEPARTMENT OF ENERGY | 2012-05-24 | — | — | US | disclosed |
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | disclosed |
| US-8129520-B2 | Methods and intermediates for the synthesis of dipyrrin-substituted porphyrinic macrocycles | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8097609-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-17 | — | — | US | disclosed |
| US-20110197969-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | UNITED STATES DEPARTMENT OF ENERGY | 2011-08-18 | — | — | US | disclosed |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-23 | — | — | US | disclosed |
| WO-2006018475-A1 | PHOTOVOLTAIC CELL BASED ON VECTORIAL ELECTRON TRANSFER | LICENTIA OY (FI) | 2006-02-23 | — | — | WO | disclosed |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | disclosed |
| WO-2004109768-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | NORTH CAROLINA STATE UNIVERSITY (US) | 2004-12-16 | — | — | WO | disclosed |
| US-20040254383-A1 | Reacting a dipyrromethane with an oxidant and a metal salt to produce the bis(dipyrrinato)metal complex; for making molecular memory devices, solar cells and light harvesting arrays | UNITED STATE DEPARTMENT OF ENERGY | 2004-12-16 | — | — | US | disclosed |
| US-20030031676-A1 | Conjugate compounds for treating atheroma and other diseases | PHARMACYCLICS, INC. | 2003-02-13 | — | — | US | disclosed |
| EP-1223982-A2 | CONJUGATE FOR TREATING ATHEROMA AND OTHER DISEASES | PHARMACYCLICS, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001032211-A2 | CONJUGATE COMPOUNDS FOR TREATING ATHEROMA AND OTHER DISEASES | PHARMACYCLICS, INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| EP-0705897-B1 | Luminescent dyes, active elements on their basis and method for measuring oxygen concentration using said luminescent dyes | JOANNEUM RESEARCH FORSCHUNGSGE (AT) | 1999-05-06 | — | — | EP | disclosed |
| US-5718842-A | MEASURING OXYGEN CONCENTRATION | JOANNEUM RESERACH FORSCHUNGSGESELLSCHAFT MBH (AT) | 1998-02-17 | — | — | US | disclosed |
| EP-0705897-A1 | Luminescent dyes, active elements on their basis and method for measuring oxygen concentration using said luminescent dyes | JOANNEUM RESEARCH Forschungsgesellschaft mbH (AT) | 1996-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126214-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | HCCS, PPOX, DHPS | STAT3 3766/4885STAT1 4231/4885TOP1 289/4885 |
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | ALK, ACVRL1, ACVR1 | STAT3 2034/4885STAT1 2300/4885TOP1 2612/4885 |
| US-20110197969-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | HCCS, PPOX, DHPS | STAT3 3766/4885STAT1 4231/4885TOP1 289/4885 |
| US-20030031676-A1 | Conjugate compounds for treating atheroma and other diseases | NQO1, AKR7A2, CYP46A1 | STAT3 3575/4885STAT1 3934/4885TOP1 316/4885 |
| US-20040254383-A1 | Reacting a dipyrromethane with an oxidant and a metal salt to produce the bis(dipyrrinato)metal complex; for making molecular memory devices, solar cells and light harvesting arrays | PPOX, NCS1, CRY1 | STAT3 750/4885STAT1 2028/4885TOP1 551/4885 |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | PPOX, ALAD, UROD | STAT3 4123/4885STAT1 4328/4885TOP1 1556/4885 |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | DHPS, NOTUM, DOHH | STAT3 4298/4885STAT1 4505/4885TOP1 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.