Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910285 | 0.84 | PARP10 (0.44) | MAPTKMT2A | |
| SCHEMBL8910755 | 0.81 | TSHR (0.33) | MAPTKMT2A | |
| SCHEMBL8148024 | 0.81 | TDP2 (0.40) | MAPTKMT2A | |
| SCHEMBL8153452 | 0.80 | LMNA (0.32) | MAPT | |
| SCHEMBL1388815 | 0.79 | MAPT (0.44) | MAPTKMT2A | |
| SCHEMBL8155023 | 0.78 | HTT (0.33) | MAPTKMT2A | |
| SCHEMBL8910407 | 0.78 | BCHE (0.39) | KMT2A | |
| SCHEMBL8910147 | 0.78 | LMNA (0.31) | MAPT | |
| SCHEMBL8540291 | 0.76 | MYC (0.33) | KMT2A | |
| SCHEMBL8153428 | 0.75 | TP53 (0.36) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0651750-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002483-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |