Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148024 | 0.87 | TDP2 (0.40) | KMT2AHTT | |
| SCHEMBL8155023 | 0.84 | HTT (0.33) | KMT2AF10HTT | |
| SCHEMBL9434751 | 0.81 | POLB (0.33) | KMT2A | |
| SCHEMBL8910285 | 0.80 | PARP10 (0.44) | KMT2AF2 | |
| SCHEMBL8909858 | 0.78 | MAPT (0.30) | KMT2A | |
| SCHEMBL8910147 | 0.78 | LMNA (0.31) | HTT | |
| SCHEMBL8910392 | 0.77 | CCNB2 (0.32) | HTT | |
| SCHEMBL8155881 | 0.77 | TDP2 (0.30) | HTT | |
| SCHEMBL8540291 | 0.76 | MYC (0.33) | KMT2A | |
| SCHEMBL8153428 | 0.75 | TP53 (0.36) | KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | claimed |
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | disclosed |