Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912815 | 0.74 | TSHR (0.57) | TYMSATM | |
| SCHEMBL8911693 | 0.74 | TTR (0.47) | DHFRNOS1GFERXDHPOLB | |
| SCHEMBL8912282 | 0.71 | DRD4 (0.43) | DHFRNOS1XDH | |
| SCHEMBL8913183 | 0.68 | DHFR (0.44) | DHFRNOS1GFERXDHPOLB | |
| SCHEMBL8912802 | 0.67 | SIRT6 (0.50) | DHFRPOLBTYMSMAPT | |
| SCHEMBL2084284 | 0.66 | ATM (0.51) | POLBATM | |
| SCHEMBL7362762 | 0.65 | HTR6 (0.55) | GLA | |
| SCHEMBL3799154 | 0.64 | LMNA (0.53) | GLAMAPTATM | |
| SCHEMBL7115197 | 0.64 | LMNA (0.53) | GLAMAPTATM | |
| Hydrochloric Acid SCHEMBL11538425 | 0.63 | ATM (0.53) | POLBGLAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670508-A | ANTITUMOR AGENTS FOR BRAIN TUMORS | NATIONAL SCIENCE COUNCIL (TW) | 1997-09-23 | — | — | US | disclosed |