SCHEMBL891207

SCHEMBL891207

c1ccc(-c2ccc3ccoc3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.48
PGR P06401 1/20 0.47
CA2 P00918 2/20 0.46
CA12 O43570 1/20 0.46
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
PTPN1 P18031 1/20 0.44
CDK9 P50750 1/20 0.43
HSD11B1 P28845 1/20 0.42
PIK3R1 P27986 1/20 0.42
PIK3CA P42336 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30646399 1.00 DYRK1A (0.48) DYRK1APGRCA2CA12ESR1
Methane SCHEMBL28138933 0.98 DYRK1A (0.47) DYRK1APGRCA2CA12ESR1
Benzofuran SCHEMBL28138904 0.94 DYRK1A (0.49) DYRK1APGRCA2CA12ESR1
SCHEMBL29756248 0.91 DYRK1A (0.50) DYRK1ACA2CA12CDK9KDM4E
SCHEMBL27341174 0.88 ACLY (0.42) DYRK1APGRCA2CA12ESR1
Benzofuran SCHEMBL28212677 0.84 CA2 (0.52) DYRK1APGRCA2CA12ESR1
SCHEMBL21500400 0.83 CA2 (0.49) DYRK1ACA2CA12CDK9HSD11B1
SCHEMBL28318294 0.83 DYRK1A (0.46) DYRK1ACA2CA12PTPN1CDK9
SCHEMBL28776100 0.83 CA2 (0.49) DYRK1APGRCA2CA12CDK9
SCHEMBL27741076 0.83 ESR1 (0.52) DYRK1AESR1ESR2HSD11B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
CN-113105496-B Method for synthesizing o-alkenylphenol derivative through nickel-catalyzed ring opening of benzofuran 华南理工大学 2022-06-14 CN disclosed
CN-113105496-A Method for synthesizing o-alkenylphenol derivative through nickel-catalyzed ring opening of benzofuran 华南理工大学 2021-07-13 CN disclosed
EP-2797862-B1 OLEFIN OLIGOMERIZATION METHODS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-04-07 EP disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
EP-2858750-B1 PHOSPHINYL GUANIDINE COMPOUNDS, CHROMIUM SALT COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-13 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
CN-106083927-B Phosphino- amidine compound, metal complex, antigravity system and their oligomeric or olefin polymerization purposes 切弗朗菲利浦化学公司 2018-10-26 CN disclosed
EP-2790828-B1 PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL CO LP (US) 2018-09-19 EP disclosed
EP-2791091-B1 PREPARATION OF CHROMIUM(III) CARBOXYLATES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2018-09-19 EP disclosed
WO-2011130170-A1 OLIGOMERIZATION OF BIS(BETA-HYDROXY) POLYSULFIDES THROUGH ETHERIFICATION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-10-20 WO disclosed
US-20110251358-A1 OLIGOMERIZATION OF BIS(BETA-HYDROXY) POLYSULFIDES THROUGH ETHERIFICATION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-10-13 US disclosed
CN-102164672-A Oligomerization catalyst system and process for oligomerizing olefins CHEVRON PHILLIPS CHEMICAL CO 2011-08-24 CN disclosed
EP-2349562-A1 OLIGOMERIZATION CATALYST SYSTEM AND PROCESS FOR OLIGOMERIZING OLEFINS Chevron Phillips Chemical Company LP (US) 2011-08-03 EP disclosed
WO-2011082192-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-07-07 WO disclosed
US-20100274065-A1 OLIGOMERIZATION CATALYST SYSTEM AND PROCESS FOR OLIGOMERIZING OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-10-28 US disclosed
US-20100113852-A1 OLIGOMERIZATION CATALYST SYSTEM AND PROCESS FOR OLIGOMERIZING OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-05-06 US disclosed
WO-2010051415-A1 OLIGOMERIZATION CATALYST SYSTEM AND PROCESS FOR OLIGOMERIZING OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-05-06 WO disclosed
EP-1183554-A1 IN-SITU RADIOACTIVITY DETECTION 3M Innovative Properties Company (US) 2002-03-06 EP disclosed
WO-2000077545-A1 IN-SITU RADIOACTIVITY DETECTION 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 DYRK1A 4395/4885PGR 3145/4885CA2 475/4885
US-20100274065-A1 OLIGOMERIZATION CATALYST SYSTEM AND PROCESS FOR OLIGOMERIZING OLEFINS DHPS, PPOX, HPD DYRK1A 1332/4885PGR 1583/4885CA2 4168/4885
US-20100113852-A1 OLIGOMERIZATION CATALYST SYSTEM AND PROCESS FOR OLIGOMERIZING OLEFINS DHPS, COG5, PPOX DYRK1A 2421/4885PGR 1661/4885CA2 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.