Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571751 | 0.89 | TLR7 (0.45) | TLR7TLR8AGTR1AGTR2 | |
| SCHEMBL7018485 | 0.87 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL7023774 | 0.85 | ALDH1A1 (0.55) | — | |
| SCHEMBL7018487 | 0.81 | AGTR1 (0.46) | TLR7AGTR1AGTR2 | |
| SCHEMBL7014033 | 0.76 | AGTR2 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7025070 | 0.76 | ENPP2 (0.52) | AGTR1AGTR2 | |
| SCHEMBL7010494 | 0.76 | TLR7 (0.43) | TLR7 | |
| SCHEMBL7011288 | 0.75 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL7017061 | 0.75 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL7015958 | 0.75 | AGTR2 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635525-A | DIAGNOSTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-03 | — | — | US | disclosed |