Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025070 | 0.91 | ENPP2 (0.52) | ALDH1A1MEN1KMT2ALMNAENPP2 | |
| SCHEMBL8912409 | 0.85 | TLR7 (0.47) | — | |
| SCHEMBL9571751 | 0.83 | TLR7 (0.45) | — | |
| SCHEMBL7850660 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ALMNAENPP2 | |
| SCHEMBL7853305 | 0.78 | AGTR1 (0.59) | ALDH1A1MEN1KMT2ALMNAENPP2 | |
| SCHEMBL7850720 | 0.76 | AGTR1 (0.62) | ALDH1A1ENPP2 | |
| SCHEMBL7018485 | 0.76 | AGTR2 (0.50) | — | |
| SCHEMBL7018487 | 0.75 | AGTR1 (0.46) | — | |
| SCHEMBL7853694 | 0.74 | AGTR1 (0.71) | ALDH1A1MEN1KMT2ALMNAENPP2 | |
| SCHEMBL8913133 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ALMNAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533058-B1 | Imidazo-fused iso- and heterocycles as angiotensin II antagonists | HOECHST AG (DE) | 2003-08-20 | — | — | EP | disclosed |
| US-5635525-A | DIAGNOSTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-03 | — | — | US | disclosed |
| WO-1997009672-A1 | TRANSPARENT SUPPORT OF PROTOCOL AND DATA COMPRESSION FEATURES FOR DATA COMMUNICATION | U.S. ROBOTICS CORPORATION (US) | 1997-03-13 | — | — | WO | disclosed |
| EP-0533058-A1 | Imidazo-fused iso- and heterocycles as angiotensin II antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |