Sugi Predict

Sugi Predict / Compounds / SCHEMBL891322

SCHEMBL891322

SCHEMBL891322

CCC(C)C=C(C=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ PGR P06401 1/20 0.39
▸ ADRA2A P08913 1/20 0.39
▸ ADRA2B P18089 1/20 0.39
▸ HTR2A P28223 1/20 0.39
▸ HRH1 P35367 1/20 0.39
▸ KCNH2 Q12809 1/20 0.39
▸ RAB9A P51151 1/20 0.38
▸ CES2 O00748 2/20 0.36
▸ CES1 P23141 2/20 0.36
▸ LMNA P02545 4/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ MMP2 P08253 1/20 0.36
▸ MMP9 P14780 1/20 0.36
▸ MMP12 P39900 1/20 0.36
▸ MMP14 P50281 1/20 0.36
▸ MMP15 P51511 1/20 0.36
▸ MMP16 P51512 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10205515 1.00 ALDH1A1 (0.39) ALDH1A1MAPK1TDP1PGRADRA2A
SCHEMBL891321 1.00 ALDH1A1 (0.39) ALDH1A1MAPK1TDP1PGRADRA2A
SCHEMBL872650 0.81 ALDH1A1 (0.45) ALDH1A1MAPK1TDP1PGRADRA2A
SCHEMBL872649 0.81 ALDH1A1 (0.45) ALDH1A1MAPK1TDP1PGRADRA2A
SCHEMBL28762549 0.77 PGR (0.39) ALDH1A1PGRADRA2AADRA2BHTR2A
SCHEMBL13696972 0.73 SMN1; SMN2 (0.44) ALDH1A1TDP1RAB9ALMNAHPGD
SCHEMBL2171580 0.73 ALDH1A1 (0.45) ALDH1A1MAPK1TDP1PGRADRA2A
SCHEMBL2171577 0.73 ALDH1A1 (0.45) ALDH1A1MAPK1TDP1PGRADRA2A
SCHEMBL891343 0.73 ALDH1A1 (0.41) ALDH1A1MAPK1TDP1PGRADRA2A
SCHEMBL2432464 0.73 ALDH1A1 (0.41) ALDH1A1MAPK1TDP1PGRADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280857-A1 DEGRADATION-RESISTANT ALDEHYDE-CONTAINING COMPOSITIONS ZOOMESSENCE INC (US) 2025-09-11 — — US claimed
CN-119136683-A Degradation resistant aldehyde-containing compositions 祖姆森斯有限公司 2024-12-13 — — CN claimed
US-20250280857-A1 DEGRADATION-RESISTANT ALDEHYDE-CONTAINING COMPOSITIONS ZOOMESSENCE INC (US) 2025-09-11 — — US disclosed
CN-119136683-A Degradation resistant aldehyde-containing compositions 祖姆森斯有限公司 2024-12-13 — — CN disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
CN-105278268-B Electrostatic charge image developing toner, electrostatic charge image developer, and toner cartridge 富士施乐株式会社 2020-05-19 — — CN disclosed
EP-2621462-B1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR PROCTER & GAMBLE (US) 2020-02-12 — — EP disclosed
US-9937115-B2 Oral care compositions with improved flavor THE PROCTER & GAMBLE COMPANY (US) 2018-04-10 — — US disclosed
US-9612542-B2 Electrostatic charge image developing toner, electrostatic charge image developer, and toner cartridge FUJI XEROX CO., LTD. (JP) 2017-04-04 — — US disclosed
CN-105278268-A Electrostatic charge image developing toner, electrostatic charge image developer, and toner cartridge FUJI XEROX CO LTD 2016-01-27 — — CN disclosed
US-20150370187-A1 ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, ELECTROSTATIC CHARGE IMAGE DEVELOPER, AND TONER CARTRIDGE FUJIFILM BUSINESS INNOVATION CORP. (JP) 2015-12-24 — — US disclosed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 — — EP disclosed
CN-103140209-A Oral care compositions with improved flavor PROCTER & GAMBLE 2013-06-05 — — CN disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 — — WO disclosed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885MAPK1 1556/4885TDP1 2650/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885MAPK1 1556/4885TDP1 2650/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885MAPK1 1556/4885TDP1 2650/4885
US-20120082628-A1 Oral Care Compositions With Improved Flavor TRPA1, TAS2R40, TAS2R30 ALDH1A1 1558/4885MAPK1 4131/4885TDP1 3315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.