Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TET3 | O43151 | 2/20 | 0.45 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.45 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.45 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447090 | 0.87 | OPRD1 (0.56) | OPRM1KMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL2918643 | 0.83 | OPRM1 (0.50) | OPRM1KMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL6248104 | 0.82 | KMT2A (0.54) | OPRM1KMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL9037444 | 0.80 | OPRD1 (0.51) | KMT2AMEN1OPRD1OPRK1TET3 | |
| SCHEMBL8353122 | 0.80 | TSHR (0.52) | OPRM1KMT2AOPRD1OPRK1TET3 | |
| SCHEMBL27472889 | 0.78 | OPRD1 (0.57) | OPRM1OPRD1OPRK1APPLMNA | |
| SCHEMBL8438413 | 0.77 | SMN1; SMN2 (0.55) | OPRM1KMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL9311071 | 0.76 | OPRM1 (0.57) | OPRM1KMT2AMEN1OPRD1OPRK1 | |
| SCHEMBL5592248 | 0.75 | OPRD1 (0.55) | OPRM1OPRD1OPRK1TSHRAPP | |
| SCHEMBL7474464 | 0.74 | APP (0.41) | KMT2AMEN1OPRD1OPRK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635510-A | TACHYKININ (ESPECIALLY SUBSTANCE P AND NEUROKININ A) ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS; NERVOUS SYSTEM DISORDERS; BRONCHODILATOR AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-03 | — | — | US | disclosed |