Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 4/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917282 | 0.90 | PLAU (0.38) | SGK1PLAUPLATAKR1C3AKR1C2 | |
| SCHEMBL8917485 | 0.89 | ALDH1A1 (0.49) | LMNAALDH1A1L3MBTL1GLAMCL1 | |
| SCHEMBL8917798 | 0.88 | MCL1 (0.47) | LMNAALDH1A1L3MBTL1GLASGK1 | |
| SCHEMBL8917459 | 0.87 | MCL1 (0.41) | LMNAALDH1A1L3MBTL1GLAMCL1 | |
| SCHEMBL8918579 | 0.86 | ALDH1A1 (0.40) | LMNAALDH1A1L3MBTL1GLAMCL1 | |
| SCHEMBL8920658 | 0.84 | ALDH1A1 (0.39) | LMNAALDH1A1L3MBTL1GLAMCL1 | |
| SCHEMBL8917188 | 0.83 | PLAU (0.48) | LMNAALDH1A1L3MBTL1PLAUPLAT | |
| SCHEMBL8916678 | 0.78 | SGK1 (0.38) | LMNAALDH1A1L3MBTL1GLASGK1 | |
| SCHEMBL8917778 | 0.77 | SGK1 (0.39) | SGK1MCL1 | |
| SCHEMBL8917334 | 0.76 | MEN1 (0.42) | LMNAALDH1A1L3MBTL1GLAPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | claimed |
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |