Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917798 | 0.91 | MCL1 (0.47) | ALDH1A1L3MBTL1LMNAGLAMCL1 | |
| SCHEMBL8917459 | 0.90 | MCL1 (0.41) | ALDH1A1L3MBTL1LMNAGLAMCL1 | |
| SCHEMBL8918579 | 0.89 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNAGLAMCL1 | |
| SCHEMBL8916678 | 0.89 | SGK1 (0.38) | ALDH1A1L3MBTL1LMNAGLAMCL1 | |
| SCHEMBL8916165 | 0.89 | LMNA (0.40) | ALDH1A1L3MBTL1LMNAGLAMCL1 | |
| SCHEMBL8920658 | 0.87 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1LMNAGLAMCL1 | |
| SCHEMBL8918537 | 0.84 | FBP1 (0.33) | ALDH1A1L3MBTL1LMNAGLAMEN1 | |
| SCHEMBL8916271 | 0.82 | CA1 (0.43) | ALDH1A1L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8917778 | 0.80 | SGK1 (0.39) | MCL1 | |
| SCHEMBL8917282 | 0.78 | PLAU (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |