Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916678 | 0.91 | SGK1 (0.38) | SGK1ALOX5APFEN1BRD4S1PR1 | |
| SCHEMBL8917459 | 0.90 | MCL1 (0.41) | ALOX5APFEN1AHRMCL1 | |
| SCHEMBL8917282 | 0.87 | PLAU (0.38) | SGK1ALOX5APFEN1BRD4SCN9A | |
| SCHEMBL8916161 | 0.83 | NR3C1 (0.44) | — | |
| SCHEMBL8919620 | 0.83 | MAPT (0.34) | SGK1 | |
| SCHEMBL8917798 | 0.82 | MCL1 (0.47) | SGK1MCL1DDR1 | |
| SCHEMBL8917485 | 0.80 | ALDH1A1 (0.49) | MCL1 | |
| SCHEMBL8918579 | 0.77 | ALDH1A1 (0.40) | MCL1 | |
| SCHEMBL8916165 | 0.77 | LMNA (0.40) | SGK1MCL1 | |
| SCHEMBL8920658 | 0.75 | ALDH1A1 (0.39) | MCL1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |