Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875576 | 0.88 | MAPT (0.49) | EGLN1MAPTCA12CA1CA2 | |
| SCHEMBL8916374 | 0.88 | ROCK2 (0.48) | MAPTCA1CA2CA9PTGS1 | |
| SCHEMBL9235404 | 0.86 | MAPT (0.46) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8867801 | 0.85 | MAPT (0.52) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8917687 | 0.85 | MAPT (0.45) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8917143 | 0.80 | LMNA (0.49) | EGLN1MAPTCA12CA1CA2 | |
| SCHEMBL9140540 | 0.80 | P4HTM (0.60) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL9139633 | 0.80 | P4HTM (0.60) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8768266 | 0.80 | ROCK2 (0.46) | MAPTCA1CA2CA9PTGS1 | |
| SCHEMBL8918674 | 0.79 | EGLN1 (0.46) | EGLN1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |