Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618859 | 0.81 | ACHE (0.65) | ALDH1A1ACHEESR2GAALMNA | |
| SCHEMBL4460667 | 0.80 | ALDH1A1 (0.52) | ALDH1A1ACHEGAALMNACES2 | |
| SCHEMBL1127542 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ACHEGAALMNACES2 | |
| SCHEMBL7810527 | 0.73 | FAAH (0.49) | ALDH1A1ACHECES2CES1SMN1; SMN2 | |
| SCHEMBL7810360 | 0.73 | ACHE (0.42) | ALDH1A1ACHEGAALMNACES2 | |
| SCHEMBL7811195 | 0.73 | CTSL (0.53) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL11535168 | 0.72 | CA2 (0.53) | ALDH1A1GAALMNASMN1; SMN2NPC1 | |
| SCHEMBL6338854 | 0.72 | CES2 (0.60) | ALDH1A1ACHELMNACES2CES1 | |
| SCHEMBL11756436 | 0.71 | CYP2A6 (0.54) | ALDH1A1CES2CES1SMN1; SMN2MEN1 | |
| SCHEMBL1127544 | 0.70 | ALDH1A1 (0.42) | ALDH1A1ACHEGAALMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684131-A | Substituted benzhydrylamines as handles for solid phase peptide synthesis | LEBL MICHAL (US) | 1997-11-04 | — | — | US | disclosed |