SCHEMBL1127544

SCHEMBL1127544

Cc1ccc(C(=S)c2ccc(S)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TDP1 Q9NUW8 3/20 0.38
ACHE P22303 2/20 0.38
PKM P14618 2/20 0.38
HTT P42858 2/20 0.38
ATM Q13315 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 2/20 0.38
NLRP1 Q9C000 1/20 0.38
GAA P10253 1/20 0.38
NTSR1 P30989 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SRD5A2 P31213 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4460667 0.87 ALDH1A1 (0.52) ALDH1A1CES2CES1LMNASMN1; SMN2
Methyl Alcohol SCHEMBL11762366 0.79 ACHE (0.53) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL72612 0.79
SCHEMBL6338854 0.78 CES2 (0.60) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL1127542 0.78 ALDH1A1 (0.44) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL9618859 0.78 ACHE (0.65) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL7810348 0.76 ACHE (0.62) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL7808794 0.76 CES2 (0.61) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL7811077 0.76 ALDH1A1 (0.62) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL1128110 0.76 ALDH1A1 (0.76) ALDH1A1CES2CES1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024579-B2 Curable liquid composition, particulate filler, and compound TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-02 US disclosed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
US-11542397-B2 Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-03 US disclosed
WO-2022210785-A1 COMPOSITION, CURED BODY, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE デンカ株式会社 2022-10-06 WO disclosed
US-11370751-B2 Sulfonium salt, heat- or photo-acid generator, heat- or photo-curable composition, and cured product thereof SAN APRO LTD. (JP) 2022-06-28 US disclosed
US-20220195097-A1 CURABLE LIQUID COMPOSITION, PARTICULATE FILLER, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2022-06-23 US disclosed
US-20220073817-A1 METHOD FOR PRODUCING QUANTUM DOT-CONTAINING FILM AND COMPOSITION FOR PRODUCING QUANTUM DOT-CONTAINING FILM TOKYO OHKA KOGYO CO., LTD. (JP) 2022-03-10 US disclosed
EP-3909943-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION San-Apro Ltd. (JP) 2021-11-17 EP disclosed
US-20210309866-A1 LIQUID COMPOSITION, QUANTUM DOT-CONTAINING FILM, OPTICAL FILM, LIGHT-EMITTING DISPLAY ELEMENT PANEL, AND LIGHT-EMITTING DISPLAY DEVICE TOKYO OHKA KOGYO CO., LTD. (JP) 2021-10-07 US disclosed
EP-2399905-B1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION SAN APRO LTD (JP) 2014-01-22 EP disclosed
US-8617787-B2 Sulfonium salt, photo-acid generator, and photosensitive resin composition SAN-APRO, LTD. (JP) 2013-12-31 US disclosed
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
EP-2399905-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION San-Apro Limited (JP) 2011-12-28 EP disclosed
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION SAN-APRO, LTD (JP) 2011-12-08 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370751-B2 Sulfonium salt, heat- or photo-acid generator, heat- or photo-curable composition, and cured product thereof TST, MPST, ASIC1 ALDH1A1 1326/4885CES2 3876/4885CES1 3442/4885
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH ALDH1A1 1481/4885CES2 1164/4885CES1 1346/4885
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST ALDH1A1 1574/4885CES2 1682/4885CES1 1649/4885
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION ASIC1, H1-0, IK ALDH1A1 2140/4885CES2 1004/4885CES1 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.