Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917171 | 0.82 | DRD2 (0.39) | MAOBDRD2SLC6A4ACHESCD | |
| SCHEMBL8919840 | 0.72 | RAB9A (0.36) | MAOBACHESCDMPO | |
| SCHEMBL2197968 | 0.71 | ACHE (0.62) | DRD2SLC6A4ACHESCD | |
| SCHEMBL8917899 | 0.71 | CYP11B1 (0.40) | DRD2SLC6A4ACHECYP11B1CYP11B2 | |
| SCHEMBL9216296 | 0.69 | MAOB (0.47) | MAOBACHENQO1 | |
| SCHEMBL8920216 | 0.66 | DRD2 (0.34) | DRD2SLC6A4ACHE | |
| SCHEMBL1845286 | 0.65 | ACHE (0.35) | DRD2SLC6A4ACHESCDMPO | |
| SCHEMBL8918420 | 0.65 | PTPN1 (0.40) | DRD2SLC6A4SCDCYP11B1CYP11B2 | |
| SCHEMBL8920018 | 0.65 | SCD (0.54) | ACHESCD | |
| SCHEMBL8917524 | 0.64 | RAB9A (0.44) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |