Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 11/20 | 0.61 |
| ▸ | PRKCB | P05771 | 11/20 | 0.61 |
| ▸ | PRKCA | P17252 | 11/20 | 0.61 |
| ▸ | PRKCE | Q02156 | 11/20 | 0.61 |
| ▸ | PRKCH | P24723 | 10/20 | 0.61 |
| ▸ | PRKCD | Q05655 | 10/20 | 0.61 |
| ▸ | CAMK2D | Q13557 | 10/20 | 0.61 |
| ▸ | CAMK2B | Q13554 | 8/20 | 0.61 |
| ▸ | CAMK2G | Q13555 | 8/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 8/20 | 0.61 |
| ▸ | PRKCZ | Q05513 | 7/20 | 0.61 |
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.40 |
| ▸ | STK16 | O75716 | 1/20 | 0.40 |
| ▸ | PAK3 | O75914 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920187 | 0.90 | PRKCG (0.59) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Hydrochloric Acid SCHEMBL8919128 | 0.89 | PRKCG (0.58) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL8921034 | 0.85 | PRKCG (0.62) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL6422277 | 0.76 | PRKCA (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL8619764 | 0.70 | CAMK2D (0.57) | PRKCACAMK2DPTPRCCDK9CDK2 | |
| SCHEMBL8427341 | 0.70 | CCNT1 (0.42) | PRKCBPRKCAPRKCEPRKCHPRKCD | |
| Hydrochloric Acid SCHEMBL8654403 | 0.69 | PTPRC (0.35) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL30358319 | 0.69 | GSK3B (0.46) | PRKCAPTPRCCDK9CDK2GSK3A | |
| SCHEMBL29447190 | 0.68 | GSK3B (0.53) | PRKCAPTPRCCDK9CDK2GSK3A | |
| SCHEMBL5957039 | 0.68 | GSK3B (0.53) | PRKCAPTPRCCDK9CDK2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672618-A | TREATING DIABETIC COMPLICATIONS | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |